Magnetic Moment Imaging, or MMI, is a non-invasive, radiation-free technique for monitoring formulations within the G.I. tract. The technique uses magnetically-tagged dosage forms and a system capable of detecting the magnetic field in the x, y and z planes.
Iron oxide (Fe3O4) is incorporated into the dosage forms which are subsequently magnetised. The magnetised dosage form can be located from the generated magnetic field, spreading from the formulation to outside the body.
Key advantages:
- does not expose subjects to radiation
- does not require magnetically shielded room
- provides real time 3-dimensional information on the movement and tumbling of formulations in the G.I. tract
- capable of detecting formulations in both the fed and fasted states
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Movement of magnetic tablet in stomach and small intestine